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Time events coding : about schizophrenic patients’disorders

LALANNE-TONGIO, Laurence (2011) Time events coding : about schizophrenic patients’disorders. Thèses de doctorat, Université de Strasbourg.

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Abstract

Psychiatrists described a temporal fragmentation at a clinical level in patients with schizophrenia. In our work, we wanted to objectify such an alteration. We measured the temporal window in 18 patients versus 18 controls. The temporal window is defined as the interval needed to discriminate the onsets of two asynchronous stimuli. We found that patients with schizophrenia have an enlarged time window. Patients thus show temporal explicit judgments impairments. These results are independent of a decision bias and are similar when targets are located across hemifields or within the same hemifield. Furthermore, we focused on patients and healthy volunteers’ responses at very short asynchronies. At short asynchronies, subjects are not able to report the asynchrony between stimuli and give the same rate of simultaneous responses as for perfect synchrony. Despite this, our results suggest an implicit processing of the asynchrony. It is as if the two stimuli are processed relative to one another in healthy volunteers, whereas patients would process each stimulus in turn: patients would process the first stimulus as isolated without taking into account the second one. We proposed that this result indicates a fragmentation in time in patients with schizophrenia. We showed that this fragmentation persists in the absence of spatial fragmentation. This fragmentation in patients might be related to a difficulty in anticipating events in time. In conclusion, we showed a dissociation between implicit and explicit disorders related to the coding of temporal events in patients with schizophrenia. These disorders might involve elementary anticipation deficits.

Item Type:Thesis
Discipline de la thèse / mémoire / rapport :Sciences du Vivant. Neurosciences
Uncontrolled Keywords:schizophrénie ; synchronie vs asynchronie ; temps implicite ; temps explicite ; codage des événements temporels ; effet Simon ; prédiction temporelle ; fenêtre temporelle
Subjects:UNERA Classification UNERA > ACT Domaine d'activité UNERA > ACT-5 Santé, industrie du médicament, cosmétique
CL Classification > DDC Dewey Decimal Classification > 600 Technologie (sciences appliquées) > 610 Médecine et santé > 616 Maladies > 616.8 Maladies du système nerveux. Neurologie. Troubles psychiques > 616.89 Troubles mentaux Schizophrénie
Classification Thèses Unistra > Santé > Médecine et odontologie > 610 Médecine et santé > 616 Maladies > 616.8 Maladies du système nerveux. Neurologie. Troubles psychiques > 616.89 Troubles mentaux Schizophrénie

UNERA Classification UNERA > DISC Discipline UNERA > DISC-16 Sciences de la vie et de la santé, psychologie
ID Code:2209
Deposited On:28 September 2011

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